United States 1926: The Dutch, 24-year-old Antonia Brico was a child when she and her parents immigrated to the United States. She dreams of becoming a conductor, but nobody takes her ambition seriously. Her piano teacher advices her against taking the entrance exam for the conservatory. Because she has little to lose, she returns to her motherland, where she begs the famous conductor Mengelberg to teach her conducting lessons. Mengelberg is not comfortable with the idea and sends her to Berlin where she, against all expectations, has a better chance as a woman to make it. Emotional strain threatens to overwhelm her, when the love of her life puts her in a difficult position. What choice will Antonia make?